Developmentally regulated interactions of liver nuclear factors with the rat phosphoenolpyruvate carboxykinase promoter
- PMID: 2325658
- PMCID: PMC360591
- DOI: 10.1128/mcb.10.5.2418-2422.1990
Developmentally regulated interactions of liver nuclear factors with the rat phosphoenolpyruvate carboxykinase promoter
Abstract
A sequential pattern of interactions of trans-acting factors in rat liver with the phosphoenolpyruvate carboxykinase promoter during late development was observed. A liver-enriched factor, possibly AF1, interacted with the promoter in fetal liver, whereas a factor with the characteristics of C/EBP bound the promoter after birth with the onset of the gene expression.
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