Spinal cord injury: harnessing spike timing to induce plastic change
- PMID: 23257186
- DOI: 10.1016/j.cub.2012.11.004
Spinal cord injury: harnessing spike timing to induce plastic change
Abstract
A recent study shows that a spike-timing-dependent plasticity protocol can potentiate corticospinal transmission to finger muscle motoneurons, in both volunteers and in patients with incomplete spinal injury. In patients, the protocol improved voluntary muscle output and performance on a peg-board test.
Copyright © 2012 Elsevier Ltd. All rights reserved.
Comment on
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Motor recovery after spinal cord injury enhanced by strengthening corticospinal synaptic transmission.Curr Biol. 2012 Dec 18;22(24):2355-61. doi: 10.1016/j.cub.2012.10.046. Epub 2012 Nov 29. Curr Biol. 2012. PMID: 23200989 Free PMC article.
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