Review
[Targeting cancer antigen (MAGE-A4, NY-ESO -1) for immunotherapy]
[Article in
Japanese]
Affiliations
- PMID: 23259384
Item in Clipboard
Review
[Targeting cancer antigen (MAGE-A4, NY-ESO -1) for immunotherapy]
[Article in
Japanese]
Nihon Rinsho.
2012 Dec.
Abstract
Cancer/testis (CT) antigen is a group of antigens that are expressed in a wide variety of malignant tumors but not in normal adult tissues except for testis. Since CT antigens are immunogenic and highly restricted to tumors, they are considered as ideal targets for cancer immunotherapy. Many clinical studies targeting CT antigens have been tested. Here we review the history and the recent progress of clinical studies targeting MAGE family and NY-ESO-1 including our trials.
Similar articles
-
Expression of the MAGE-A4 and NY-ESO-1 cancer-testis antigens and T cell infiltration in non-small cell lung carcinoma and their prognostic significance.Int J Oncol. 2006 May;28(5):1089-98. Int J Oncol. 2006. PMID: 16596224
-
Expression of the MAGE-A4 and NY-ESO-1 cancer-testis antigens in serous ovarian neoplasms.Clin Cancer Res. 2003 Dec 15;9(17):6453-60. Clin Cancer Res. 2003. PMID: 14695148
-
Cancer/testis antigen expression and autologous humoral immunity to NY-ESO-1 in gastric cancer.Cancer Immun. 2004 Nov 1;4:11. Cancer Immun. 2004. PMID: 15516106
-
[NY-ESO-1 and cancer immunotherapy].Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2008 Aug;30(4):371-7. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2008. PMID: 18795604 Review. Chinese.
-
MAGE-A family: attractive targets for cancer immunotherapy.Vaccine. 2011 Nov 3;29(47):8496-500. doi: 10.1016/j.vaccine.2011.09.014. Epub 2011 Sep 18. Vaccine. 2011. PMID: 21933694 Review.
Cited by
-
Recent Trends in Biosensing and Diagnostic Methods for Novel Cancer Biomarkers.Biosensors (Basel). 2023 Mar 18;13(3):398. doi: 10.3390/bios13030398. Biosensors (Basel). 2023. PMID: 36979610 Free PMC article. Review.
-
T cell receptor mimic antibodies for cancer therapy.Oncoimmunology. 2015 Jun 1;5(1):e1049803. doi: 10.1080/2162402X.2015.1049803. eCollection 2016. Oncoimmunology. 2015. PMID: 26942058 Free PMC article. Review.
-
Opportunities and Challenges for Antibodies against Intracellular Antigens.Theranostics. 2019 Oct 15;9(25):7792-7806. doi: 10.7150/thno.35486. eCollection 2019. Theranostics. 2019. PMID: 31695801 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Research Materials