[Microcolorimetric study of the association of trypsin with a pancreatic inhibitor]
[Article in
Russian]
- PMID: 2326
Item in Clipboard
[Microcolorimetric study of the association of trypsin with a pancreatic inhibitor]
[Article in
Russian]
Biokhimiia.
1975 Sep-Oct.
Abstract
Enthalpy of the association of trypsin with pancreatic inhibitor from bovine pancreas at 25 degrees C as a function of pH and ionic strength is estimated. The dependence of the enthalpy on pH is of an extremal character with a minimum at pH 7.6 (delta H degrees =-10.3 ccal/mole). The increase of ionic strength with the addition of LiCl, KCl and CsCl at pH 7.6 leads to be increase of delta H degrees. Possible mechanisms of enthlpy changes depending on medium conditions are considered.
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