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Comment
. 2012 Dec 21;151(7):1401-3.
doi: 10.1016/j.cell.2012.12.007.

Blending hippo and WNT: sharing messengers and regulation

Becky P Tsai  1 , Nate P Hoverter, Marian L Waterman
Affiliations
Free article
Comment

Blending hippo and WNT: sharing messengers and regulation

Becky P Tsai et al. Cell. .
Free article

Abstract

Two new studies reveal ways in which the Wnt pathway commandeers Hippo components for signaling. Azzolin et al. show how the Hippo transcription factor TAZ mediates Wnt signals, and Rosenbluh et al. show how β-catenin and YAP1 form a kinase-regulated complex with transcription factor TBX5.

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Comment on

  • Role of TAZ as mediator of Wnt signaling.
    Azzolin L, Zanconato F, Bresolin S, Forcato M, Basso G, Bicciato S, Cordenonsi M, Piccolo S. Azzolin L, et al. Cell. 2012 Dec 21;151(7):1443-56. doi: 10.1016/j.cell.2012.11.027. Epub 2012 Dec 13. Cell. 2012. PMID: 23245942

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