Treatment options for diffuse diabetic macular edema

Abstract

Purpose: To describe the current management of diffuse diabetic macular edema (DDME).

Methods: Review and discussion of the literature regarding DDME.

Results: Diffuse diabetic macular edema is a condition that can be managed by means of several treatment options, including focal/grid laser photocoagulation, intravitreal or periocular corticosteroids, intravitreal anti-vascular endothelial growth factor (VEGF), and vitrectomy with or without internal limiting membrane peeling.

Conclusions: Even though there is no randomized clinical trial specifically designed to assess the best treatment approach for DDME, new therapeutic approaches based on intravitreal injections of corticosteroid and anti-VEGF molecules offer new hope for its management.