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. 2012 Dec 30;68(52):10640-10664.
doi: 10.1016/j.tet.2012.07.090. Epub 2012 Aug 7.

Advances in the chemistry of β-lactam and its medicinal applications

Anushree Kamath  1 , Iwao Ojima
Affiliations

Advances in the chemistry of β-lactam and its medicinal applications

Anushree Kamath et al. Tetrahedron. .
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Mechanism of Staudinger [2+2] ketene-imine cycloaddition
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Figure 2
Type 1 and Type 2 asymmetric alkylations
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Figure 3
Chemical structures of paclitaxel and docetaxel
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Cryptophycins
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Conformationally constrained non-peptide b-turn mimics
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Figure 6
Combretastatin A-4, its derivative and b-lactam-based mimics
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Figure 7
Rational design of b-lactam based LHRH receptor antagonists
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Scheme 53
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References

    1. Georg GI. The Organic Chemistry of β-Lactams and references cited therein. VCH; New York: 1992.
    1. Aoki H, Sakai H, Kohsaka M, Konomi T, Hosoda J. J Antibiotics. 1976;29:890–901. - PubMed
    1. Hashimoto M, Komori T, Kamiya T. J Am Chem Soc. 1976;98:3023–3025. - PubMed
    1. Imada A, Kitano K, Kintaka K, Muroi M, Asai M. Nature. 1981;289:590–591. - PubMed
    1. Ojima I, Shimizu N, Qiu X, Chen HJC, Nakahashi K. Bull Soc Chim France. 1987:649–658.

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