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Review
. 2013 Jan;7(1):35-40.
doi: 10.1586/egh.12.67.

Helicobacter pylori infection in Japan

Seiji Shiota  1 , Kazunari Murakawi, Rumiko Suzuki, Toshio Fujioka, Yoshio Yamaoka
Affiliations
Review

Helicobacter pylori infection in Japan

Seiji Shiota et al. Expert Rev Gastroenterol Hepatol. 2013 Jan.

Abstract

The prevalence of Helicobacter pylori infection is gradually decreasing in Japan. On the main island of Japan, nearly all H. pylori isolates possess cagA and vacA with strong virulence. However, less virulent H. pylori strains are frequently found in Okinawa where cases of gastric cancer are the lowest in Japan. Eradication therapy for peptic ulcer, idiopathic thrombocytopenic purpura, gastric mucosa-associated lymphoid tissue lymphoma and early gastric cancer after endoscopic resection has been approved by the Japanese national health insurance system. However, the Japanese Society for Helicobacter Research recently stated that all 'H. pylori infection' was considered as the indication for eradication irrespective of the background diseases. To eliminate H. pylori in Japan, the Japanese health insurance system should approve the eradication of all H. pylori infections.

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Conflict of interest statement

Financial & competing interests disclosure

The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript.

Figures

Figure 1
Figure 1
Prevalence of Helicobacter pylori infection in Japan.
See this image and copyright information in PMC

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