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Randomized Controlled Trial
. 2013 Oct;30(9):715-22.
doi: 10.1055/s-0032-1331027. Epub 2012 Dec 27.

The obstetric and neonatal implications of a low value on the 50-g glucose screening test

Kimberly K Ma  1 , Lisa Mele, Mark B Landon, Catherine Y Spong, Susan M Ramin, Brian Casey, Ronald J Wapner, Michael W Varner, Dwight J Rouse, John M Thorp Jr, Anthony Sciscione, Patrick Catalano, Margaret Harper, George Saade, Steve N Caritis, Yoram Sorokin, Alan M Peaceman; Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network
Collaborators, Affiliations
Randomized Controlled Trial

The obstetric and neonatal implications of a low value on the 50-g glucose screening test

Kimberly K Ma et al. Am J Perinatol. 2013 Oct.

Abstract

Objective: To assess the relationship between a low 50-g 1-hour glucose loading test (GLT) and maternal and neonatal outcomes in women without diabetes.

Study design: This was a secondary analysis of a multicenter observational cohort from a randomized trial of treatment for mild gestational diabetes. Maternal and neonatal outcomes were compared between women with GLT values < 90 mg/dL and those with results 90 to 119 mg/dL.

Results: Of 436 enrolled women, 297 (68.1%) had a GLT result of 90 to 119 mg/dL and 139 (31.9%) had a result of < 90 mg/dL. There was a lower incidence of neonatal hypoglycemia in those with a GLT < 90 mg/dL (5.7% versus 16.5%, p = 0.006). Other outcomes were not associated with test results.

Conclusion: A GLT result < 90 mg/dL compared with 90 to 119 mg/dL is associated with a lower risk of neonatal hypoglycemia, but no other significant findings.

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