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Case Reports
. 2013 Mar;57(3):1561-2.
doi: 10.1128/AAC.02298-12. Epub 2012 Dec 28.

Complete sequence of an IncN plasmid, pIMP-HZ1, carrying blaIMP-4 in a Klebsiella pneumoniae strain associated with medical travel to China

Wai-U Lo, Yuk-Yam Cheung, Eileen Lai, David Lung, Tak-Lun Que, Pak-Leung Ho
Case Reports

Complete sequence of an IncN plasmid, pIMP-HZ1, carrying blaIMP-4 in a Klebsiella pneumoniae strain associated with medical travel to China

Wai-U Lo et al. Antimicrob Agents Chemother. 2013 Mar.
No abstract available

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Figures

Fig 1
Fig 1
Comparative analysis of linear plasmid maps for three IncN plasmids (R46, pIMP-HZ1, p12), one IncHIB/FIB plasmid (pKOX_R1), and the partially sequenced plasmid fragment pIMP4. The functional blocks for the IncN plasmids are indicated above the linear maps. R46 is used as the IncN reference. White boxes indicate the plasmid scaffold regions. Pink circles indicate the origin of transfer (oriT). The tra genes are indicated in capital letters inside the box. Hatched boxes indicate open reading frames (ORFs) in pIMP-HZ1 with no homologues in R46. Blue boxes indicate genes in the conserved upstream (CUP)-controlled regulon. Purple boxes indicate the fipA and nuc genes. Green boxes indicate the mobile elements. Red boxes indicate the resistance genes. The inverted triangle above p12 represents an 8.7-kb block (tnpA-rec-arsC-arsB-arsA-arsD-arsR) that was inserted into traB. Areas shaded in gray indicate homologies in the plasmid scaffold regions. All genes in the three IncN plasmids are shown, but the genes and regions in the maps are not drawn exactly in proportion to the length of the sequences.
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