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. 1990 Apr;99(4 Pt 1):286-7.
doi: 10.1177/000348949009900407.

Human leukocyte antigens -A, -B, -C, and -DR and nasopharyngeal carcinoma in northern China

X N Zhu  1 , R Chen, F H Kong, W Liu
Affiliations

Human leukocyte antigens -A, -B, -C, and -DR and nasopharyngeal carcinoma in northern China

X N Zhu et al. Ann Otol Rhinol Laryngol. 1990 Apr.

Abstract

We observed HLA associations in patients with nasopharyngeal carcinoma from northern China. There was an increased risk of nasopharyngeal carcinoma associated with HLA-B35 and a difference in the HLA association between patients with early- and late-onset disease. The frequency of B35 was significantly higher in patients than in control subjects, especially in early-onset patients (less than 30 years old). Late-onset patients had a higher frequency of DR2 as compared with normal subjects.

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