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Review
. 2012 Jul;53(7):754-61.

Laboratory test descriptions for bovine respiratory disease diagnosis and their strengths and weaknesses: gold standards for diagnosis, do they exist?

Robert W Fulton  1 , Anthony W Confer
Affiliations
Review

Laboratory test descriptions for bovine respiratory disease diagnosis and their strengths and weaknesses: gold standards for diagnosis, do they exist?

Robert W Fulton et al. Can Vet J. 2012 Jul.

Abstract
in English, French

The diagnosis of bovine respiratory diseases (BRD) poses significant challenges to the clinician as there are numerous infectious etiologies, operating singly or most often in combination. Clinical signs alone may not be diagnostic and the diagnostic laboratory is often used to assist the clinician. Recently many molecular-based tests have been taken from the research laboratory to the veterinary diagnostic laboratory. This review describes the "traditional tests" and several "molecular tests" and discusses the benefits and limitations of the tests and their interpretation. Clinicians should consult with their diagnostic laboratory regarding the interpretation of the test results. The rate of development and use of molecular diagnostic tests have outpaced validation, standardization, and standards for interpretation relative to their use in BRD diagnostics.

Description des tests de laboratoire pour le diagnostic des maladies respiratoires bovines et de leurs forces et faiblesses : les étalons or pour le diagnostic existent-ils? Le diagnostic des maladies respiratoires bovines (MRB) suscite des défis importants pour le clinicien, car il existe de nombreuses étiologies infectieuses, qui opèrent seules ou le plus souvent en combinaison. Les signes cliniques seuls peuvent ne pas permettre un diagnostic et le laboratoire de diagnostic est souvent utilisé pour assister le clinicien. Récemment, de nombreux tests moléculaires ont été empruntés au laboratoire de recherche pour utilisation dans le laboratoire de diagnostic vétérinaire. Cet article décrit les ≪tests traditionnels≫ et plusieurs ≪tests moléculaires≫ et analyse les avantages et les limitations des tests et de leur interprétation. Les cliniciens devraient consulter leur laboratoire de diagnostic concernant l’interprétation des résultats des tests. La vitesse de développement et l’utilisation des tests diagnostiques moléculaires ont dépassé la validation, la normalisation et les normes pour l’interprétation relativement à leur utilisation dans les diagnostics des maladies respiratoires bovines.

(Traduit par Isabelle Vallières)

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