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. 2013 Feb;40(1):39-45.
doi: 10.1111/iji.12028. Epub 2012 Dec 26.

16(th) IHIW: population global distribution of killer immunoglobulin-like receptor (KIR) and ligands

J A Hollenbach  1 , D G Augusto, C Alaez, L Bubnova, I Fae, G Fischer, F F Gonzalez-Galarza, C Gorodezky, L Karabon, P Kusnierczyk, J Noble, O Rickards, C Roberts, M Schaffer, L Shi, S Tavoularis, E Trachtenberg, Y Yao, D Middleton
Affiliations

16(th) IHIW: population global distribution of killer immunoglobulin-like receptor (KIR) and ligands

J A Hollenbach et al. Int J Immunogenet. 2013 Feb.

Abstract

In the last fifteen years, published reports have described KIR gene-content frequency distributions in more than 120 populations worldwide. However, there have been limited studies examining these data in aggregate to detect overall patterns of variation at regional and global levels. Here, we present a summary of the collection of KIR gene-content data for 105 worldwide populations collected as part of the 15th and 16th International Histocompatibility and Immunogenetics Workshops, and preliminary results for data analysis.

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Figures

Figure 1
Figure 1
Global distribution of 16th IHIW populations
Figure 2
Figure 2
A clustered heat map of KIR carrier frequencies in the 16th IHIW populations. Populations are ordered generally by distance from Africa.
Figure 3
Figure 3
HLA-C group and KIR2DL2L3 frequencies are highly correlated within populations.
See this image and copyright information in PMC

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