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. 2011;33(2):155-7.
doi: 10.5581/1516-8484.20110038.

Histiocytic sarcoma

Eduardo Silva Machado  1 , Ana Carolina de Miranda, Ticiane Escopelli, Ruggero Caron, Alessandra Cristhina Escopelli
Affiliations

Histiocytic sarcoma

Eduardo Silva Machado et al. Rev Bras Hematol Hemoter. 2011.

Abstract

A 59-year-old white woman, SC, after being treated for pneumonia, presented with an increase in the size of lymph nodes. The immunohistochemical examination diagnosed histiocytic sarcoma. Relapse occurred 12 months after starting chemotherapy. The patient evolved with febrile neutropenia, septic shock and death.

Keywords: Case report; Histiocytic sarcoma/diagnosis; Neoplasms.

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Conflict of interest statement

Conflict-of-interest disclosure: The authors declare no competing financial interest

Figures

Figure 1
Figure 1
Immunohistochemical study proved to be positive for CD68. Immunophenotyping confirms the histiocytic lineage through an overexpression of the CD68 antigen
Figure 2
Figure 2
Immunohistochemical study showing atypical histiocytic proliferation, diffuse proliferation of large cells with irregular nuclei, conspicuous nucleoli and abundant cytoplasm
See this image and copyright information in PMC

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