Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2012 Nov 1;68(Pt 11):o3185.
doi: 10.1107/S1600536812042912. Epub 2012 Oct 20.

(+)-(1S,5R,6R)-6-[(S)-1-Hy-droxy-2-(meth-oxy-meth-yloxy)eth-yl]-1-methyl-3-trichloro-methyl-2-aza-4,7-dioxa-bicyclo-[3.3.0]oct-2-en-8-one

Takeshi Oishi  1 , Hiroki Oishi, Syun Tsuzaki, Takaaki Sato, Noritaka Chida
Affiliations

(+)-(1S,5R,6R)-6-[(S)-1-Hy-droxy-2-(meth-oxy-meth-yloxy)eth-yl]-1-methyl-3-trichloro-methyl-2-aza-4,7-dioxa-bicyclo-[3.3.0]oct-2-en-8-one

Takeshi Oishi et al. Acta Crystallogr Sect E Struct Rep Online. .

Abstract

In the title compound, C(11)H(14)Cl(3)NO(6), the fused five-membered oxazoline and tetra-hydro-furan rings are essentially planar with maximum deviations of 0.069 (1) and 0.031 (1) Å, respectively, and make a dihedral angle of 64.23 (11)° with each other. In the crystal, mol-ecules are linked by O-H⋯O and C-H⋯O hydrogen bonds, forming chains along the b-axis direction. Further C-H⋯O hydrogen bonds are observed between the chains.

PubMed Disclaimer

Figures

Fig. 1.
Fig. 1.
The molecular structure of the title compound, with atom labels and 50% probability displacement ellipsoids for non-H atoms.
Fig. 2.
Fig. 2.
The crystal packing of the title compound, viewed down the a axis. The dashed lines indicate O—H···O hydrogen bonds.
See this image and copyright information in PMC

References

    1. Bruker (2012). APEX2, SAINT and SADABS Bruker AXS Inc., Madison, Wisconsin, USA.
    1. Flack, H. D. (1983). Acta Cryst. A39, 876–881.
    1. Horn, W. S., Smith, J. L., Bills, G. F., Raghoobar, S. L., Helms, G. L., Kurts, M. B., Marrinan, J. A., Frommer, B. R., Thornton, R. A. & Mandala, S. M. (1992). J. Antibiot. 45, 1692–1696. - PubMed
    1. Macrae, C. F., Edgington, P. R., McCabe, P., Pidcock, E., Shields, G. P., Taylor, R., Towler, M. & van de Streek, J. (2006). J. Appl. Cryst. 39, 453–457.
    1. Oishi, H., Tsuzaki, S., Sato, T. & Chida, N. (2012). In preparation.