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Case Reports
. 2012 Nov;6(9):1564-5.
doi: 10.7860/JCDR/2012/4632.2563.

A rare cause of gastric perforation-Candida infection: a case report and review of the literature

Nalini Gupta  1
Affiliations
Case Reports

A rare cause of gastric perforation-Candida infection: a case report and review of the literature

Nalini Gupta. J Clin Diagn Res. 2012 Nov.

Abstract

Fungal microorganisms as a cause of gastric perforation, is very rare. Most of the cases of gastric perforation are seen as the complications of peptic ulcer disease, the intake of NSAIDs (Non Steroidal Anti-Inflammatory Drugs), neoplastic diseases, etc. We are reporting a case of a 50 year old male who presented with a sudden onset of abdominal pain and shock and was diagnosed as acute peritonitis which was caused by a gastrointestinal perforation. An emergency exploratory laporotomy was performed and a gastric perforation repair with omentoplexy was done. However, the patient died in the post operative period due to a sudden cardiac arrest. A gastric perforation edge biopsy revealed the presence of fungal hyphae. The peritoneal fluid culture revealed Candida albicans colonies.

Keywords: Candida perforation; Fungal infection; Gastric perforation.

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Figures

[Table/Fig-1]
[Table/Fig-1]
Light microscopy from perforation edge biopsy revealed fungal hyphae (H& E X 10)
[Table/Fig-2]
[Table/Fig-2]
Light microscopy showing entangled fungal hyphae (PAS stain X 40)
See this image and copyright information in PMC

References

    1. Bakhshi GD, Borisa AD, Shaikh AS, Thadeshwar NR, Kher Y, Kapadnis LA, et al. Invasive gastric candidiasis with perforation. Bombay Hospital Journal. 2011;53(2):264–65.
    1. Pugh TF, Fitch SJ. Invasive gastric candidiasis. Pediatric Radiology. 1986;16:67–68. - PubMed
    1. Gock M, Schafer M, Perren A, Demartines N, Clavien PA. A fatal oesophageal perforation which was caused by invasive Candidiasis. Ann Thoracic Surg. 2005;80:1120–22. - PubMed
    1. Tran HA, Vincent J, Slavin M, Griggs A. Esophageal perforation which was secondary to angioinvasive Candida glabrata following a hemopoitic stem cell transplantation. Clinical microbiology and infection. 2003;9:1215–18. - PubMed
    1. Ginnis MR. Mycetoma. Dermatol Clin. 1996;14(1):97–104. - PubMed

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