Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Aug;12(4):456-9.
doi: 10.1007/s12311-012-0435-x.

Somatosensory temporal discrimination threshold is increased in patients with cerebellar atrophy

Fiore Manganelli  1 , Raffaele Dubbioso, Chiara Pisciotta, Antonella Antenora, Maria Nolano, Giuseppe De Michele, Alessandro Filla, Alfredo Berardelli, Lucio Santoro
Affiliations

Somatosensory temporal discrimination threshold is increased in patients with cerebellar atrophy

Fiore Manganelli et al. Cerebellum. 2013 Aug.

Abstract

Processing of time in the millisecond range seems to depend on cerebellar function and it can be assessed by using the somatosensory temporal discrimination threshold testing. No studies have yet investigated this temporal discrimination task in patients with cerebellar atrophy. Eleven patients with degenerative cerebellar ataxia and 11 controls underwent somatosensory temporal discrimination threshold evaluation. The degree of cerebellar dysfunction was measured by the International Cooperative Ataxia Rating Scale. Somatosensory temporal discrimination threshold was higher in patients compared to controls for each stimulated site (hand, neck, and eye). Age, disease duration, and International Cooperative Ataxia Rating Scale scores were not correlated to somatosensory temporal discrimination threshold. Somatosensory temporal discrimination threshold is abnormal in patients with cerebellar atrophy. These findings suggest that the cerebellum plays a role in modulating the somatosensory temporal discrimination threshold and confirm the role of cerebellum in the processing of time in the millisecond range.

PubMed Disclaimer

References

    1. J Neurosci. 2004 Mar 10;24(10):2585-91 - PubMed
    1. Acta Neuropathol. 2012 Jul;124(1):1-21 - PubMed
    1. J Neurol Sci. 2007 Dec 15;263(1-2):107-12 - PubMed
    1. Acta Neurol Scand. 2012 Nov;126(5):344-9 - PubMed
    1. Brain. 2004 Mar;127(Pt 3):561-74 - PubMed