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Comment
. 2013 Jan 3;12(1):1-3.
doi: 10.1016/j.stem.2012.12.005.

Metabolic makeover for HSCs

Matthew R Warr  1 , Emmanuelle Passegué
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Free article
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Metabolic makeover for HSCs

Matthew R Warr et al. Cell Stem Cell. .
Free article

Abstract

Hematopoietic stem cells (HSCs) must at times exit quiescence to divide and produce differentiated blood cells. In this issue of Cell Stem Cell, Takubo et al. (2013) and Yu et al. (2013) show that these opposing actions require distinct metabolic programs to meet the changing energy demands of self-renewing HSCs.

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