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. 2013 Jan;4(1):41-43.
doi: 10.1136/flgastro-2012-100241. Epub 2012 Sep 5.

Value of drug level testing and antibody assays in optimising biological therapy

Affiliations

Value of drug level testing and antibody assays in optimising biological therapy

Séverine Vermeire et al. Frontline Gastroenterol. 2013 Jan.
No abstract available

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Figures

Figure 1
Figure 1
Algorithm in patients under anti- tumour necrosis factor (anti-TNF) who present with symptoms suggestive of loss of response.

References

    1. Allez M, Karmiris K, Louis E, et al. Report of the ECCO pathogenesis workshop on anti-TNF therapy failures in inflammatory bowel diseases: definitions, frequency and pharmacological aspects. J Crohns Colitis 2010;4:355–66. - PubMed
    1. Baert F, Noman M, Vermeire S, et al. Influence of immunogenicity on the long-term efficacy of infliximab in Crohn's disease. N Engl J Med 2003;348:601–8. - PubMed
    1. Schnitzler F, Fidder H, Ferrante M, et al. Long-term outcome of treatment with infliximab in 614 patients with Crohn's disease: results from a single-centre cohort. Gut 2009;58:492–500. - PubMed
    1. Maser EA, Villela R, Silverberg MS, et al. Association of trough serum infliximab to clinical outcome after scheduled maintenance treatment for Crohn's disease. Clin Gastroenterol Hepatol 2006;4:1248–54. - PubMed
    1. Seow CH, Newman A, Irwin SP, et al. Trough serum infliximab: a predictive factor of clinical outcome for infliximab treatment in acute ulcerative colitis. Gut 2010;59:49–54. - PubMed