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Case Reports
. 2013 Jun;45(6):494-6.
doi: 10.3109/00365548.2012.755268. Epub 2013 Jan 7.

A severe case of Puumala hantavirus infection successfully treated with bradykinin receptor antagonist icatibant

Jaakko Antonen  1 , Ilona Leppänen, Jyrki Tenhunen, Pertti Arvola, Satu Mäkelä, Antti Vaheri, Jukka Mustonen
Affiliations
Case Reports

A severe case of Puumala hantavirus infection successfully treated with bradykinin receptor antagonist icatibant

Jaakko Antonen et al. Scand J Infect Dis. 2013 Jun.

Abstract

A patient with severe capillary leakage syndrome caused by a Puumala hantavirus infection was treated with a single dose of icatibant, a bradykinin receptor antagonist, with a dramatic positive response. We suggest that this drug should be tested in a larger number of patients with severe hantavirus infection.

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