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Comment
. 2013 Jan 7;17(1):401.
doi: 10.1186/cc11888.

Hypernatremia and intracranial pressure: more questions than answers

Donald E G Griesdale, Mypinder S Sekhon, William R Henderson
Comment

Hypernatremia and intracranial pressure: more questions than answers

Donald E G Griesdale et al. Crit Care. .

Abstract

The observational literature suggests that hypernatremia is associated with worse outcomes in patients with traumatic brain injury. In a previous issue of Critical Care, Wells and colleagues add to this literature by failing to show an association between hypernatremia and reduced intracranial pressure. However, we must bear in mind many limitations of observational methods before eliminating hyperosmolar therapy from our armamentarium.

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Comment in

  • Authors' response.
    Wells DL, Swanson JM, Wood GC, Magnotti LJ, Boucher BA, Croce MA, Harrison CG, Muhlbauer MS, Fabian TC. Wells DL, et al. Crit Care. 2013;17(1):401. Crit Care. 2013. PMID: 25215361 No abstract available.

Comment on

References

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