Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2012 Dec;67(12):1407-14.
doi: 10.6061/clinics/2012(12)10.

Effects of Brazilian Cardioprotective Diet Program on risk factors in patients with coronary heart disease: a Brazilian Cardioprotective Diet randomized pilot trial

Bernardete Weber  1 , Andrea Polo Galante, Angela Cristine Bersch-Ferreira, Camila Ragne Torreglosa, Vitor Oliveira Carvalho, Elivane da Silva Victor, Jose Amalth do Espírito-Santo, Maria Beatriz Ross-Fernandes, Rafael Marques Soares, Rosana Perim Costa, Enilda de Sousa Lara, Anna Maria Buehler, Otávio Berwanger
Affiliations
Randomized Controlled Trial

Effects of Brazilian Cardioprotective Diet Program on risk factors in patients with coronary heart disease: a Brazilian Cardioprotective Diet randomized pilot trial

Bernardete Weber et al. Clinics (Sao Paulo). 2012 Dec.

Abstract

Objective: To evaluate the effectiveness of the Brazilian Cardioprotective Diet Program in reducing blood pressures, fasting glucose levels and body mass indices in patients with established atherothrombotic disease.

Method: This randomized controlled pilot trial included outpatients who were over 45 years of age with atherothrombotic cardiovascular disease. Group A, who received the Brazilian Cardioprotective Diet Program, had weekly sessions with dietitians. Groups B and C received the usual dietary therapy that is given to patients with cardiovascular diseases as proposed by the Brazilian guidelines. This diet had the same nutrient profile as that given to Group A, but it was customized by the integration of typical Mediterranean foods. The difference between Groups B and C was the number of sessions with the dietitian. Group B received weekly sessions, while group C only had monthly sessions. ClinicalTrials.gov: NCT 01453166.

Results: There was a greater reduction in systolic (7.8%) and diastolic (10.8%) blood pressures in Group A compared with Group B (2.3% and 7.3%), and Group C (3.9% and 4.9%, respectively). Fasting glucose decreased by 5.3% and 2% in Groups A and B, respectively. Fasting glucose increased by 3.7% in Group C. The BMIs decreased by 3.5% and 3.3% in Groups A and B, respectively. Group C did not present with any changes in BMI. However, none of these data showed statistical differences between the groups, which is methodologically acceptable in pilot trials.

Conclusions: The Brazilian Cardioprotective Diet Program seems to be more effective in reducing blood pressures, fasting glucose levels, weights and BMIs in patients with previous cardiovascular disease compared with the diet that has been proposed by the Brazilian guidelines.

Trial registration: ClinicalTrials.gov NCT01453166.

PubMed Disclaimer

Conflict of interest statement

No potential conflict of interest was reported.

Figures

Figure 1
Figure 1
Flow diagram of the participants in the study.
Figure 2
Figure 2
Mean and standard deviation of outcomes in Groups A, B, and C.
See this image and copyright information in PMC

Comment in

References

    1. World Health Organization. Mortality estimates by cause, age, and sex for the year 2008. 2011. Geneva: WHO
    1. Hooper L, Griffiths E, Abrahams B, Alexander W, Atkins S, Atkinson G, et al. Dietetic guidelines: diet in secondary prevention of cardiovascular disease (first update, June 2003) J Hum Nutr Diet. 2004;17(4):337–49. - PubMed
    1. Appel LJ, Sacks FM, Carey VJ, Obarzanek E, Swain JF, Miller ER, III, et al. Effects of protein, monounsaturated fat, and carbohydrate intake on blood pressure and serum lipids: results of the Omni Heart randomized trial. JAMA. 2005;294(19):2455–64. - PubMed
    1. Parikh P, McDaniel MC, Ashen MD, Miller JI, Sorrentino M, Chan V, et al. Diets and cardiovascular disease: an evidence-based assessment. J Am Coll Cardiol. 2005;45:1379–87. - PubMed
    1. Willett WC, Sacks F, Trichopoulou A, Drescher G, Ferro-Luzzi A, Helsing E, et al. Mediterranean diet pyramid: a cultural model for healthy eating. Am J Clin Nutr. 1995;61(6 Suppl) :1402S–6S. - PubMed

Publication types

Associated data