Limitations of the pig-to-non-human primate islet transplantation model
- PMID: 23297811
- PMCID: PMC3778665
- DOI: 10.1111/xen.12017
Limitations of the pig-to-non-human primate islet transplantation model
Comment on
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The usefulness and limitations of the diabetic macaque model in evaluating long-term porcine islet xenograft survival.Xenotransplantation. 2013 Jan-Feb;20(1):5-17. doi: 10.1111/xen.12012. Epub 2012 Nov 29. Xenotransplantation. 2013. PMID: 23190260 Review.
References
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- Cooper DKC, Bottino R, Satyananda V, Wijkstrom M, Trucco M. Towards clinical islet xenotransplantation: are revisions to the IXA guidelines warranted? (Commentary) Xenotransplantation. 2013 In press. - PubMed
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- Casu A, Bottino R, Balamurugan AN, et al. Metabolic aspects of pig-to-monkey (Macaca fascicularis) islet transplantation: implications for translation into clinical practice. Diabetologia. 2008;51:120–129. - PubMed
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- Graham ML, Bellin MD, Papas KK, Hering BJ, Schuurman HJ. Species incompatibilities in the pig-to-macaque islet xenotransplant model affect transplant outcome: a comparison with allotransplantation. Xenotransplantation. 2011;18:328–342. - PubMed
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- Bennet W, Sundberg B, Lundgren T, et al. Damage to porcine islets of Langerhans after exposure to human blood in vitro or after intraportal transplantation to cynomologus monkeys: protective effects of sCR1 and heparin. Transplantation. 2000;69:711–719. - PubMed
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