Review
The heart in diabetes mellitus. Part I. Biochemical basis for myocardial dysfunction
- PMID: 233046
Item in Clipboard
Review
The heart in diabetes mellitus. Part I. Biochemical basis for myocardial dysfunction
S Afr Med J.
.
Abstract
The heart in acutely diabetic animals is subject to multiple inhibitions of glucose metabolism caused by enhanced metabolism of free fatty acids (FFA) and ketone bodies. Such metabolic changes may impair the reaction of the diabetic heart to oxygen lack. In chronically diabetic hearts the increased deposition of triglycerides in the heart and the formation of glycoproteins may underlie the newly recognized clinical entity of diabetic cardiomyopathy.
Similar articles
-
Heart triglycerides in health and disease.Recent Adv Stud Cardiac Struct Metab. 1973;3:179-204. Recent Adv Stud Cardiac Struct Metab. 1973. PMID: 4619694 Review. No abstract available.
-
The heart in diabetes.West J Med. 1984 Apr;140(4):583-93. West J Med. 1984. PMID: 6372249 Free PMC article. Review.
-
Green tea extract impedes dyslipidaemia and development of cardiac dysfunction in streptozotocin-diabetic rats.Clin Exp Pharmacol Physiol. 2006 Dec;33(12):1184-9. doi: 10.1111/j.1440-1681.2006.04509.x. Clin Exp Pharmacol Physiol. 2006. PMID: 17184499
-
Diabetic heart disease.J Assoc Physicians India. 1984 Mar;32(3):273-7. J Assoc Physicians India. 1984. PMID: 6378878 Review. No abstract available.
-
Metabolic therapy for patients with diabetes mellitus and coronary artery disease.Am J Cardiol. 2006 Sep 4;98(5A):14J-18J. doi: 10.1016/j.amjcard.2006.07.004. Epub 2006 Jul 24. Am J Cardiol. 2006. PMID: 16931201 Review.
Cited by
-
Inhibition by adenosine triphosphate of heart microsomal neutral lipase activity.Lipids. 1983 Jun;18(6):408-11. doi: 10.1007/BF02535426. Lipids. 1983. PMID: 6877046
-
Mechanisms of subcellular remodeling in heart failure due to diabetes.Heart Fail Rev. 2014 Jan;19(1):87-99. doi: 10.1007/s10741-013-9385-8. Heart Fail Rev. 2014. PMID: 23436108 Review.
-
Coronary blood flow in chronic insulin-dependent diabetic dogs.Acta Diabetol Lat. 1989 Oct-Dec;26(4):275-82. doi: 10.1007/BF02624638. Acta Diabetol Lat. 1989. PMID: 2629449
-
Glycolysis and glucose oxidation in the rat heart under nonrecirculating perfusion conditions.Basic Res Cardiol. 1984 May-Jun;79(3):307-12. doi: 10.1007/BF01908031. Basic Res Cardiol. 1984. PMID: 6383335