Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2012 Dec;78(6):94-8.
doi: 10.5935/1808-8694.20120040.

[Pharyngocutaneous fistula following total laryngectomy]

[Article in Portuguese]
Affiliations

[Pharyngocutaneous fistula following total laryngectomy]

[Article in Portuguese]
Felipe Toyama Aires et al. Braz J Otorhinolaryngol. 2012 Dec.

Abstract

Pharyngocutaneous fistula (PCF) is the most common complication after total laryngectomy.

Objectives: To establish the incidence of this complication and to analyze the predisposing factors.

Method: This is a cross-sectional study of a historical cohort including 94 patients who underwent total laryngectomy. The following aspects were correlated to the occurrence of PCF: gender, age, tumor site, TNM staging, type of neck dissection, previous radiation therapy, previous tracheotomy, and use of stapler for pharyngeal closure. The following were considered in PCF cases: the day into postoperative care when the fistula was diagnosed, duration of occurrence, and proposed treatment.

Results: Twenty (21.3%) patients had PCF. The incidence of PCF was statistically higher in T4 tumors when compared to T2 and T3 neoplasms (p = 0.03). The other analyzed correlations were not statistically significant. However, 40.9% of the patients submitted to tracheostomy previously had fistulae, against 21.1% of the patients not submitted to this procedure.

Conclusion: Advanced primary tumor staging is correlated with higher incidences of PCF.

PubMed Disclaimer

Similar articles

Cited by

References

    1. Cavalot AL, Gervasio CF, Nazionale G, Albera R, Bussi M, Staffieri A, et al. Pharyngocutaneous fistula as a complication of total laryngectomy: review of the literature and analysis of case records. Otolaryngol Head Neck Surg. 2000;123(5):587–592. - PubMed
    1. Saydam L, Kalcioglu T, Kizilay A. Early oral feeding following total laryngectomy. Am J Otolaryngol. 2002;23(5):277–281. - PubMed
    1. Bresson K, Rasmussen H, Rasmussen PA. Pharyngo-cutaneous fistulae in totally laryngectomized patients. J Laryngol Otol. 1974;88(9):835–842. - PubMed
    1. Thawley SE. Complications of combined radiation therapy and surgery for carcinoma of the larynx and inferior hypopharynx. Laryngoscope. 1981;91(5):677–700. - PubMed
    1. Virtaniemi JA, Kumpulainen EJ, Hirvikoski PP, Johansson RT, Kosma VM. The incidence and etiology of postlaryngectomy pharyngocutaneous fistulae. Head Neck. 2001;23(1):29–33. - PubMed

Publication types