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Case Reports
. 2013 Jan 9:2013:bcr2012006672.
doi: 10.1136/bcr-2012-006672.

Severe CMV complication following maintenance therapy with rituximab

Lenaïg Le Clech  1 , Jean-Christophe Ianotto, Isabelle Quintin-Roue, Adrian Tempescul
Affiliations
Case Reports

Severe CMV complication following maintenance therapy with rituximab

Lenaïg Le Clech et al. BMJ Case Rep. .

Abstract

Cytomegalovirus (CMV) encephalitis is a rare infection that immunodeficient patients, mainly where HIV-positive, may suffer from. Several cases were described when complications with the treatment with monoclonal antibodies, like rituximab, for malignant lymphomas. We will describe here the case of a patient, who has developed CMV gastritis, then CMV encephalitis after the treatment of a CLL with a chemotherapy and maintenance therapy with rituximab.

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Figures

Figure 1
Figure 1
Image of tumoral lesion (left) and images of typical viral inclusions (right) in cytomegalovirus reactivation in patients treated with rituximab maintenance.
See this image and copyright information in PMC

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