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Comment
. 2013 Jan 8;21(1):4-6.
doi: 10.1016/j.str.2012.12.006.

Single-stranded nucleic acid recognition: is there a code after all?

Antoine Cléry  1 , Julien Boudet  1 , Frédéric H-T Allain  2
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Single-stranded nucleic acid recognition: is there a code after all?

Antoine Cléry et al. Structure. .
Free article

Abstract

Proteins that bind single-stranded nucleic acids have crucial roles in cells, and structural analyses have contributed to a better understanding of their functions. In this issue of Structure, Dickey and colleagues describe several high resolution structures of a single OB-fold bound to different single-stranded DNA (ssDNA) sequences and reveal a spectacular co-adaptability of the protein/ssDNA interactions.

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