Neonatal abstinence syndrome: treatment and pediatric outcomes
- PMID: 23314720
- PMCID: PMC3589586
- DOI: 10.1097/GRF.0b013e31827feea4
Neonatal abstinence syndrome: treatment and pediatric outcomes
Abstract
Recent rise in rates of opiate replacement therapy among pregnant women have resulted in increasing number of infants requiring treatment for neonatal abstinence syndrome (NAS). Short-term and long-term developmental outcomes associated with prenatal opiate exposure are discussed, including symptoms and severity of NAS, and early cognitive and motor delays. Maternal and infant risk factors are discussed, and include patterns of maternal substance use during pregnancy, genetic risk, polysubstance exposure pharmacological treatment for NAS and breastfeeding. The importance of characterizing corollary environmental risk factors is also considered.
References
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- NSDUH. National Survey on Drug Use and Health: National Findings. 2008
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- TEDS; DHHS, OSA. Treatment Episode Data Set (TEDS) 2007.
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- Oei J, Lui K. Management of the newborn infant affected by maternal opiates and other drugs of dependency. Journal of Paediatrics and Child Health. 2007;43(1–2):9–18. - PubMed
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- McCarthy JJ. Intrauterine abstinence syndrome (IAS) during buprenorphine inductions and methadone tapers: Can we assure the safety of the fetus? J Matern-Fetal Neo M. 2012;25(2):109–112. - PubMed
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