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Review

. 2012 Oct;1(5):e002642.

doi: 10.1161/JAHA.112.002642. Epub 2012 Oct 25.

Heuristic methods for finding pathogenic variants in gene coding sequences

Monique Ohanian¹, Robyn Otway, Diane Fatkin

Affiliations

PMID: 23316295
PMCID: PMC3541611
DOI: 10.1161/JAHA.112.002642

Review

Heuristic methods for finding pathogenic variants in gene coding sequences

Monique Ohanian et al. J Am Heart Assoc. 2012 Oct.

. 2012 Oct;1(5):e002642.

doi: 10.1161/JAHA.112.002642. Epub 2012 Oct 25.

Authors

Monique Ohanian¹, Robyn Otway, Diane Fatkin

Affiliation

¹ Molecular Cardiology Division, Victor Chang Cardiac Research Institute, Sydney, New South Wales, Australia.

PMID: 23316295
PMCID: PMC3541611
DOI: 10.1161/JAHA.112.002642

No abstract available

Keywords: cardiovascular disease; genetic variants; nonsynonymous; prediction.

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Figures

Figure 1. — Figure 1.
Flow chart showing steps for DNA sequence analysis. ESP indicates Exome Sequencing Project; 1000G, 1000 Genomes project.

See this image and copyright information in PMC

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