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Comment
. 2013 Feb;133(2):285-6.
doi: 10.1038/jid.2012.441.

Retinoids putting the "a" in alopecia

Phillip D Holler  1 , George Cotsarelis
Affiliations
Free article
Comment

Retinoids putting the "a" in alopecia

Phillip D Holler et al. J Invest Dermatol. 2013 Feb.
Free article

Abstract

Vitamin A (vitA) has many roles in human biology. With respect to hair, knockout mice for vitA receptor, hairless, and vitamin D genes have similar phenotypes, and follicle loss occurs during catagen. Hypovitaminosis A from inadequate vitA intake causes hair loss. This work suggests that dietary vitA may have a role in precipitating and maintaining alopecias as well.

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  • Endogenous retinoids in the pathogenesis of alopecia areata.
    Duncan FJ, Silva KA, Johnson CJ, King BL, Szatkiewicz JP, Kamdar SP, Ong DE, Napoli JL, Wang J, King LE Jr, Whiting DA, McElwee KJ, Sundberg JP, Everts HB. Duncan FJ, et al. J Invest Dermatol. 2013 Feb;133(2):334-43. doi: 10.1038/jid.2012.344. Epub 2012 Sep 27. J Invest Dermatol. 2013. PMID: 23014334 Free PMC article.
  • Retinoid metabolism is altered in human and mouse cicatricial alopecia.
    Everts HB, Silva KA, Montgomery S, Suo L, Menser M, Valet AS, King LE, Ong DE, Sundberg JP. Everts HB, et al. J Invest Dermatol. 2013 Feb;133(2):325-33. doi: 10.1038/jid.2012.393. Epub 2012 Oct 25. J Invest Dermatol. 2013. PMID: 23096705 Free PMC article.

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