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. 2012 Dec 20;8(6):978-82.
doi: 10.5114/aoms.2012.30948. Epub 2012 Oct 8.

Lyme disease: review

Grażyna Biesiada  1 , Jacek Czepiel, Maciej R Leśniak, Aleksander Garlicki, Tomasz Mach
Affiliations

Lyme disease: review

Grażyna Biesiada et al. Arch Med Sci. .

Abstract

Lyme disease is a multi-organ animal-borne disease, caused by spirochetes of Borrelia burgdorferi (Bb), which typically affect the skin, nervous system, musculoskeletal system and heart. A history of confirmed exposure to tick bites, typical signs and symptoms of Lyme borreliosis and positive tests for anti-Bb antibodies, are the basis of a diagnosis. A two-step diagnosis is necessary: the first step is based on a high sensitivity ELISA test with positive results confirmed by a more specific Western blot assay. Antibiotic therapy is curative in most cases, but some patients develop chronic symptoms, which do not respond to antibiotics. The aim of this review is to summarize our current knowledge of the symptoms, clinical diagnosis and treatment of Lyme borreliosis.

Keywords: Lyme borreliosis; borreliosis; tick.

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