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. 2012:2012:725735.
doi: 10.1155/2012/725735. Epub 2012 Dec 24.

The management of pregnancy in women with hepatocellular adenoma: a plea for an individualized approach

Mirelle E E Bröker  1 , Jan N M Ijzermans, Susanna M van Aalten, Robert A de Man, Türkan Terkivatan
Affiliations

The management of pregnancy in women with hepatocellular adenoma: a plea for an individualized approach

Mirelle E E Bröker et al. Int J Hepatol. 2012.

Abstract

Because of the risk of hormone-induced growth and spontaneous rupture of hepatocellular adenoma (HCA) during pregnancy, special considerations are required. Due to the scarcity of cases, there is no evidence-based algorithm for the evaluation and management of HCA during pregnancy. We think it should be questioned if it is justified to discourage pregnancy in all women with HCA. The biological behavior of this benign lesion might be less threatening than presumed and a negative advice concerning pregnancy has great impact on the lives of these young female patients. The balance between the pros and cons of hepatic adenomas and pregnancy should be reconsidered. In our center, pregnancy in women with an HCA up to 5 cm is no longer discouraged in close consultation with the patient, her partner, and members of the liver expert team.

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Figures

Figure 1
Figure 1
Flowchart for women with a HCA and a wish for pregnancy.
Figure 2
Figure 2
An example of a woman with a HCA of 4.2 cm in segment 2/3 in which pregnancy will not be discouraged.
See this image and copyright information in PMC

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