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. 2012:2012:927305.
doi: 10.1155/2012/927305. Epub 2012 Dec 23.

Olmsted syndrome

Renata Elise Tonoli  1 , Damiê De Villa, Renata Hübner Frainer, Luana Pizzarro Meneghello, Nelson Ricachnevsky, Maurício de Quadros
Affiliations

Olmsted syndrome

Renata Elise Tonoli et al. Case Rep Dermatol Med. 2012.

Abstract

Olmsted syndrome is a rare congenital, sharply circumscribed transgredient palmoplantar keratoderma. It was first described by Olmsted in 1927. The diagnosis of this rare disease depends on clinical features like symmetrical involvement of keratoderma of the palms and soles and the symmetrical hyperkeratotic plaques around the body orifices. It starts in the neonatal period or in childhood. The disease has a slow but progressive and extremely disabling course. Treatment of Olmsted syndrome is often based on topical therapy with retinoic acid, corticosteroid, emollients, and keratolytics. The present paper describes a case of Olmsted syndrome and its treatment.

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Figures

Figure 1
Figure 1
Plantar keratoderma.
Figure 2
Figure 2
Erythema and fissured fingers.
Figure 3
Figure 3
Diffuse alopecia.
Figure 4
Figure 4
Nail dystrophy.
Figure 5
Figure 5
Hyperkeratotic plaque on chin, perioral fissures.
Figure 6
Figure 6
Perianal plaque.
Figure 7
Figure 7
Histopathological exam.
Figure 8
Figure 8
Improvement of perianal hyperkeratotic plaque after treatment.
See this image and copyright information in PMC

Comment in

  • Comment on "Olmsted Syndrome".
    Gatault S, Kirby B, Danso-Abeam D. Gatault S, et al. Case Rep Dermatol Med. 2020 Jun 3;2020:8024981. doi: 10.1155/2020/8024981. eCollection 2020. Case Rep Dermatol Med. 2020. PMID: 32566327 Free PMC article. No abstract available.

References

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