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. 2012:2012:352401.
doi: 10.1155/2012/352401. Epub 2012 Dec 19.

A Case of Squamous Cell Carcinoma of the Renal Pelvis in association with Schistosoma hematobium

Muhammad A A Khan  1 , Ashok Kar, Marjorie M Walker, Jo Lloyd, Justin A Vale, Erik K Mayer
Affiliations

A Case of Squamous Cell Carcinoma of the Renal Pelvis in association with Schistosoma hematobium

Muhammad A A Khan et al. Case Rep Oncol Med. 2012.

Abstract

A 72-year-old man presented with painless frank haematuria. Investigations included intravenous urogram and abdominal/pelvic CT which revealed a marked focal thickening of the wall of the inferior aspect of the left renal pelvis extending into the lower pole calyx and into the pelviureteric junction resulting in left hydronephrosis. Urine cytology demonstrated clusters of malignant keratinised squamous cells and schistosome ova. He underwent left laparoscopic radical nephroureterectomy and histology revealed moderately differentiated keratinising squamous cell carcinoma in the renal pelvis.

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Figures

Figure 1
Figure 1
Intravenous urogram demonstrating dilatation of the left PC system with blunting and fullness of the calyces. There is an unusual crescentic shape enhancement seen inferiorly at the left renal pelvis.
Figure 2
Figure 2
Computed tomography scan showing marked focal thickening of the wall of the inferior aspect of the left renal pelvis extending into the lower pole calyx and into the pelviureteric junction resulting in left hydronephrosis.
Figure 3
Figure 3
Urine cytology specimen showing (a) clusters of keratinised malignant squamous cells and (b) Schistosoma egg, probably with a terminally located spine.
Figure 4
Figure 4
Lower pole of the left kidney largely replaced by a white friable tumour which appears to arise from the pelvicalyceal mucosa at the hilum. The tumour focally extends into hilar and perinephric fat.
See this image and copyright information in PMC

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