The yin and yang of cystic fibrosis transmembrane conductance regulator function: implications for chronic lung disease
- PMID: 23322792
- PMCID: PMC3570650
- DOI: 10.1164/rccm.201211-2011ED
The yin and yang of cystic fibrosis transmembrane conductance regulator function: implications for chronic lung disease
Comment on
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Neutrophil elastase degrades cystic fibrosis transmembrane conductance regulator via calpains and disables channel function in vitro and in vivo.Am J Respir Crit Care Med. 2013 Jan 15;187(2):170-9. doi: 10.1164/rccm.201205-0875OC. Epub 2012 Dec 6. Am J Respir Crit Care Med. 2013. PMID: 23220915
References
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- Di A, Brown ME, Deriy LV, Li C, Szeto FL, Chen Y, Huang P, Tong J, Naren AP, Bindokas V, et al. CFTR regulates phagosome acidification in macrophages and alters bactericidal activity. Nat Cell Biol 2006;8:933–944 - PubMed
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