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Comment
. 2013 Jan 17;17(1):105.
doi: 10.1186/cc11907.

A new role for statins in sepsis

Jean-Sebastien Rachoin, Elizabeth Cerceo, R Phillip Dellinger
Comment

A new role for statins in sepsis

Jean-Sebastien Rachoin et al. Crit Care. .

Abstract

Several studies have shown promising results regarding the use of statins as an adjunctive treatment for sepsis. Most of those studies were retrospective or observational in nature. The ASEPSIS trial has reported that the administration of atorvastatin reduced clinical progression of sepsis but did not improve mortality. These findings are promising and further multicenter trials are needed to confirm these outcomes and to establish whether this class of medications will offer utility in this regard.

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