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Case Reports
. 2013 Mar;88(3):575-7.
doi: 10.4269/ajtmh.12-0563. Epub 2013 Jan 16.

Hemophagocytic lymphohistiocytosis associated with visceral leishmaniasis in late adulthood

Guilherme Grossi Lopes Cançado  1 , Guilherme Gomes Freitas, Flavia Helena Fidelis Faria, Antonio Vaz de Macedo, Vandack Nobre
Affiliations
Case Reports

Hemophagocytic lymphohistiocytosis associated with visceral leishmaniasis in late adulthood

Guilherme Grossi Lopes Cançado et al. Am J Trop Med Hyg. 2013 Mar.

Abstract

We describe a case of hemophagocytic lymphohistiocytosis related to visceral leishmaniasis in late adulthood. Because clinical features of visceral leishmaniasis can mimic those of hemophagocytic lymphohistiocytosis, diagnosing leishmaniasis as the underlying etiology can be quite challenging. In our case, treatment with amphotericin B resulted in a dramatic resolution of clinical abnormalities.

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Figures

Figure 1.
Figure 1.
Wright-Giemsa stained bone marrow aspirate (1000×) showing: A, hemophagocytosis of a mitotic erythroblast; B, atypical tetranucleated plasmacyte; C, Amastigote form of Leishmania.
See this image and copyright information in PMC

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