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. 1990 Apr;28(4):825-7.
doi: 10.1128/jcm.28.4.825-827.1990.

Rapid diagnosis of typhoid fever through identification of Salmonella typhi within 18 hours of specimen acquisition by culture of the mononuclear cell-platelet fraction of blood

F A Rubin  1 , P D McWhirter, D Burr, N H Punjabi, E Lane, S Kumala, P Sudarmono, S P Pulungsih, M Lesmana, P Tjaniadi, et al.
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Rapid diagnosis of typhoid fever through identification of Salmonella typhi within 18 hours of specimen acquisition by culture of the mononuclear cell-platelet fraction of blood

F A Rubin et al. J Clin Microbiol. 1990 Apr.

Abstract

Detection of Salmonella typhi in blood by culture of the mononuclear cell-platelet layer was compared with other methods currently used for the diagnosis of typhoid fever. Colonies of S. typhi were present in all mononuclear cell-platelet layer-positive cultures within 18 h of plating and were identified within an additional 10 min by a coagglutination technique. In contrast, identification of all positive cultures by conventional blood culture required 3 days.

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References

    1. Lancet. 1975 May 31;1(7918):1211-3 - PubMed
    1. J Clin Microbiol. 1979 Mar;9(3):391-6 - PubMed
    1. Trans R Soc Trop Med Hyg. 1979;73(6):680-3 - PubMed
    1. Southeast Asian J Trop Med Public Health. 1980 Dec;11(4):441-5 - PubMed
    1. Adv Immunol. 1982;33:307-51 - PubMed

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