Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Jan 16;33(3):855-62.
doi: 10.1523/JNEUROSCI.2861-12.2013.

Polio, still lurking in the shadows

Affiliations

Polio, still lurking in the shadows

Anthony N van den Pol. J Neurosci. .
No abstract available

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Photo showing polio patients at Rancho Los Amigos National Rehabilitation Center in California in 1953. Used with permission of Rancho Los Amigos.
Figure 2.
Figure 2.
On the left is a schematic representation of the positive strand RNA genome of poliovirus. This is translated into a single polyprotein, which is then cleaved into a number of poliovirus proteins. In the upper right, a model of poliovirus is seen, with the four capsid proteins combining to form the elements of the virus capsid.
Figure 3.
Figure 3.
A transmission electron micrograph shows the 30 nm poliovirus particles. Courtesy of the US Centers for Disease Control.

Similar articles

Cited by

References

    1. Abe Y, Fujii K, Nagata N, Takeuchi O, Akira S, Oshiumi H, Matsumoto M, Seya T, Koike S. The toll-like receptor 3-mediated antiviral response is important for protection against poliovirus infection in poliovirus receptor transgenic mice. J Virol. 2012;86:185–194. - PMC - PubMed
    1. Autret A, Martin-Latil S, Mousson L, Wirotius A, Petit F, Arnoult D, Colbère-Garapin F, Estaquier J, Blondel B. Poliovirus induces Bax-dependent cell death mediated by c-Jun NH2-terminal kinase. J Virol. 2007;81:7504–7516. - PMC - PubMed
    1. Baury B, Masson D, McDermott BM, Jr, Jarry A, Blottière HM, Blanchardie P, Laboisse CL, Lustenberger P, Racaniello VR, Denis MG. Identification of secreted CD155 isoforms. Biochem Biophys Res Commun. 2003;309:175–182. - PubMed
    1. Berger MM, Kopp N, Vital C, Redl B, Aymard M, Lina B. Detection and cellular localization of enterovirus RNA sequences in spinal cord of patients with ALS. Neurology. 2000;54:20–25. - PubMed
    1. Bledsoe AW, Jackson CA, McPherson S, Morrow CD. Cytokine production in motor neurons by poliovirus replicon vector gene delivery. Nat Biotechnol. 2000;18:964–969. - PubMed

Publication types

LinkOut - more resources