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. 2013 Mar 1;288(9):6679-87.
doi: 10.1074/jbc.X113.453894. Epub 2013 Jan 16.

Fifty years excitement with science: recollections with and without tRNA

Richard Giegé  1
Affiliations

Fifty years excitement with science: recollections with and without tRNA

Richard Giegé. J Biol Chem. .
No abstract available

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Figures

FIGURE 1.
FIGURE 1.
R. G. (right) at MIT with Alex Rich (left) and Tom RajBhandary (middle) on the occasion of Alex's eightieth birthday party (June 10, 2005).
FIGURE 2.
FIGURE 2.
The yeast tRNAAsp structure displayed in our homemade Richard's box, as was usual in the old days. Behind the tRNA model, the picture shows, from left to right, Jean-Claude Thierry, R. G., Marie-Bernard Comarmond (a doctoral student at the time and now a CNRS scientist in Paris), and Dino Moras.
FIGURE 3.
FIGURE 3.
Jean-Pierre Ebel, Dieter Söll, Dino Moras, and Marianne Grunberg-Manago (from left to right) before a rafting party near Umeå, Sweden, on the occasion of the twelfth tRNA Workshop (July 1987). The tradition at the tRNA Workshops was always to mix scientific, cultural, and even sports events. Sadly, the tRNA family is missing Jean-Pierre Ebel (1920–1992) and Marianne Grunberg-Manago (1921–2013); they were beloved mentors.
FIGURE 4.
FIGURE 4.
R. G. with Dorothy Hodgkin, Madeleine Riès-Kautt, and a student (from left to right) at ICCBM2. This conference was the real beginning of the ICCBM series and gathered an interdisciplinary community of biologists, physicists, chemists, and engineers interested in crystals made of biological entities. It also provided an opportunity to young scientists, including students, to participate for the first time in an international conference outside of their home country, as was the case for Marat Yusupov from Pushchino and several other Russian attendees. Dorothy gave a great lecture on her first steps with protein crystals and structural biology; it was wonderful to see how she interacted with the students and how she communicated to everybody her enthusiasm for science.
FIGURE 5.
FIGURE 5.
My team in 1992 in front of the IBMC. First row from left to right: Magali Frugier, Joëlle Rudinger, Frédérique Pêche, Marie-Hélène Mazauric, Ya-Ming Hou (a visitor from Paul Schimmel's laboratory at MIT), and Bernard Lorber; second row from left to right: Daniel Kern, Joern Pütz, Anne Dietrich, Brice Felden, and Catherine Florentz.
See this image and copyright information in PMC

References

    1. Giegé R., Ebel J.-P. (1968) Integrity of the terminal pCpCpA sequence of tRNA extracts from yeast at various stages of growth [in French] Biochim. Biophys. Acta 161, 125–136 - PubMed
    1. Giegé R. (1972) Study on the specificity of recognition of transfer ribonucleic acids by aminoacyl-tRNA synthetases [in French]. Thèse de Doctorat d'Etat, Université Louis Pasteur, Strasbourg, France
    1. Lengyel P. (1966) Problems in protein biosynthesis. J. Gen. Physiol. 49, 305–330 - PMC - PubMed
    1. de Duve C. (1988) The second genetic code. Nature 333, 117–118 - PubMed
    1. Schimmel P., Giegé R., Moras D., Yokoyama S. (1993) An operational RNA code for amino acids and possible relationship to genetic code. Proc. Natl. Acad. Sci. U.S.A. 90, 8763–8768 - PMC - PubMed

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