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Review
. 1979 Jul 12;280(5718):109-16.
doi: 10.1038/280109a0.

Hormonal regulation of peptide receptors and target cell responses

K J Catt, J P Harwood, G Aguilera, M L Dufau
Review

Hormonal regulation of peptide receptors and target cell responses

K J Catt et al. Nature. .

Abstract

Regulation of plasma membrane receptors for peptide hormones by the prevailing ligand concentration often causes altered target cell function. Receptor number is determined by hormone-induced changes in membrane conformation, irreversible ligand binding, and processing of ligand-receptor complexes during hormone action.

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