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. 2012:2012:283946.
doi: 10.1155/2012/283946. Epub 2012 Dec 23.

Van der woude syndrome associated with hypodontia: a rare clinical entity

Romesh Soni  1 , Rajul Vivek, Adit Srivastava, Ankita Singh, Shalabh Srivastava, T P Chaturvedi
Affiliations

Van der woude syndrome associated with hypodontia: a rare clinical entity

Romesh Soni et al. Case Rep Dent. 2012.

Abstract

Van der Woude syndrome (VWS) is usually underreported and frequently not diagnosed. The phenomenon that cleft lip and palate are regularly combined in the same pedigree makes it unique. A meticulous examination of a patient with lip pits may reveal a hidden form of a cleft, for example, submucous. This paper presents a case of VWS in a ten-year-old boy with characteristic orofacial features. Special emphasis has also been given on the need for appropriate genetic counseling.

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Figures

Figure 1
Figure 1
Maxillary central incisors hanging down along with premaxilla and bilateral pits in lower lip—frontal view.
Figure 2
Figure 2
Intraoral view showing bilateral alveolar clefts in premaxillary region.
Figure 3
Figure 3
OPG disclosing missing bilateral maxillary lateral incisor tooth germ.
See this image and copyright information in PMC

References

    1. Sarode GS, Desai RS, Sarode SC, Kulkarni MA. Van der woude syndrome with an unusual intraoral finding. Indian Journal of Dental Research. 2011;22(1):164–165. - PubMed
    1. Arangannal P, Muthu MS, Nirmal L. Van der Woude syndrome: a case report. Journal of the Indian Society of Pedodontics and Preventive Dentistry. 2002;20(3):102–103. - PubMed
    1. Gorlin RJ, Cohen MM Jr., Levin LS, editors. Syndromes of the Head and Neck. 3rd edition. New York, NY, USA: Oxford University Press; 1990.
    1. Nagore E, Sánchez-Motilla JM, Febrer MI, Serrano G, Bonillo J, Aliaga A. Congenital lower lip pits (Van der Woude syndrome): presentation of 10 cases. Pediatric Dermatology. 1998;15(6):443–445. - PubMed
    1. Cervenka J, Gorlin RJ, Anderson VE. The syndrome of pits of the lower lip and cleft lip and/or palate. Genetic considerations. American Journal of Human Genetics. 1967;19(3):416–432. - PMC - PubMed

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