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Multicenter Study
. 2013 Jan 18;15(1):9.
doi: 10.1186/1532-429X-15-9.

European Cardiovascular Magnetic Resonance (EuroCMR) registry--multi national results from 57 centers in 15 countries

Oliver Bruder  1 , Anja Wagner, Massimo Lombardi, Jürg Schwitter, Albert van Rossum, Günter Pilz, Detlev Nothnagel, Henning Steen, Steffen Petersen, Eike Nagel, Sanjay Prasad, Julia Schumm, Simon Greulich, Alessandro Cagnolo, Pierre Monney, Christina C Deluigi, Thorsten Dill, Herbert Frank, Georg Sabin, Steffen Schneider, Heiko Mahrholdt
Affiliations
Multicenter Study

European Cardiovascular Magnetic Resonance (EuroCMR) registry--multi national results from 57 centers in 15 countries

Oliver Bruder et al. J Cardiovasc Magn Reson. .

Abstract

Background: The EuroCMR registry sought to evaluate indications, image quality, safety and impact on patient management of clinical routine CMR in a multi-national European setting. Furthermore, interim analysis of the specific protocols should underscore the prognostic potential of CMR.

Methods: Multi-center registry with consecutive enrolment of patients in 57 centers in 15 countries. More than 27000 consecutive patients were enrolled.

Results: The most important indications were risk stratification in suspected CAD/Ischemia (34.2%), workup of myocarditis/cardiomyopathies (32.2%), as well as assessment of viability (14.6%). Image quality was diagnostic in more than 98% of cases. Severe complications occurred in 0.026%, always associated with stress testing. No patient died during or due to CMR. In 61.8% CMR findings impacted on patient management. Importantly, in nearly 8.7% the final diagnosis based on CMR was different to the diagnosis before CMR, leading to a complete change in management. Interim analysis of suspected CAD and risk stratification in HCM specific protocols revealed a low rate of adverse events for suspected CAD patients with normal stress CMR (1.0% per year), and for HCM patients without LGE (2.7% per year).

Conclusion: The most important indications in Europe are risk stratification in suspected CAD/Ischemia, work-up of myocarditis and cardiomyopathies, as well as assessment of viability. CMR imaging is a safe procedure, has diagnostic image quality in more than 98% of cases, and its results have strong impact on patient management. Interim analyses of the specific protocols underscore the prognostic value of clinical routine CMR in CAD and HCM.

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Figures

Figure 1
Figure 1
Political map of Europe visualizing all 57 participating centers in 15 countries.
Figure 2
Figure 2
Kaplan-Meier Survival Curves for the specific protocol “suspected CAD” with regard to death, aborted SCD and non-fatal myocardial infarction. The number of patients at risk is shown at the bottom of the figure.
Figure 3
Figure 3
Kaplan-Meier Survival Curves for the specific protocol “risk stratification HCM” with regard to death, aborted SCD and adequate ICD discharge. The number of patients at risk is shown at the bottom of the figure.
See this image and copyright information in PMC

References

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