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. 2013 Feb 25;49(16):1654-6.
doi: 10.1039/c3cc38764j.

Pd(II)-catalyzed decarboxylative acylation of phenylacetamides with α-oxocarboxylic acids via C-H bond activation

Jihye Park  1 , Minyoung Kim, Satyasheel Sharma, Eonjeong Park, Aejin Kim, Sang Hwi Lee, Jong Hwan Kwak, Young Hoon Jung, In Su Kim
Affiliations

Pd(II)-catalyzed decarboxylative acylation of phenylacetamides with α-oxocarboxylic acids via C-H bond activation

Jihye Park et al. Chem Commun (Camb). .

Abstract

A palladium-catalyzed decarboxylative acylation of phenylacetamides with α-oxocarboxylic acids via C-H bond activation is described. This protocol provides efficient access to a range of ortho-acyl phenylacetamides, which can be easily converted to 3-isochromanone derivatives.

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