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Review
. 2013 Feb;125(3-4):61-70.
doi: 10.1007/s00508-012-0221-2. Epub 2013 Jan 19.

Neurotoxic effects of nonylphenol: a review

Xu Jie  1 , Li Jianmei, Feng Zheng, Gong Lei, Zhang Biao, Yu Jie
Affiliations
Review

Neurotoxic effects of nonylphenol: a review

Xu Jie et al. Wien Klin Wochenschr. 2013 Feb.

Abstract

Nonylphenol (NP), identified as an environmental endocrine disruptor, used as important raw materials for detergents, emulsifiers, and wetting agents in industry and is also found in paints, pesticides, and household toiletries. NP has been reported to have deleterious effects on central nervous system (CNS) other than reproductive and immune systems including disrupting neuroendocrine homeostasis, altering cognitive function, and neurotoxicity of tissues, etc., particularly when NP's disruption occurs during critical developmental window of brain. This review will discuss the evidence for environmental endocrine disruption of NP and the sequelae on endocrine, reproductive and nerve functions, as well as causal relationships between endocrine disruption and cognitive behavior effects.

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