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Review
. 2013 Jan 16;4(1):22-5.
doi: 10.1021/cn300224n.

Serotonin neuron diversity in the dorsal raphe

Rodrigo Andrade  1 , Samir Haj-Dahmane
Affiliations
Review

Serotonin neuron diversity in the dorsal raphe

Rodrigo Andrade et al. ACS Chem Neurosci. .

Abstract

The dorsal raphe nucleus contains one of the largest groups of serotonergic neurons in the mammalian brain and is the main site of origin of the serotonergic projection to the cerebral cortex. Early electrophysiological studies suggested that serotonergic neurons in this cell group formed a homogeneous cell class. More recent studies however have reported heterogeneity among the core anatomical and electrophysiological properties of these neurons, thus raising the possibility that serotonergic neurons of this cell group may form two or more distinct cell classes. In this Viewpoint, we review these findings and suggest ways to look at cellular heterogeneity among serotonergic neurons.

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Figures

Figure 1
Figure 1
Tryptophan hydroxylase immunohistochemical localization of serotonergic neurons in the mouse DRN.
See this image and copyright information in PMC

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