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Comment
. 2013 Jan 21;17(1):106.
doi: 10.1186/cc11899.

A week seems to be weak: tailoring duration of antibiotic treatment in Gram-negative ventilator-associated pneumonia

Ignacio Martin-Loeches, Antoni Torres
Comment

A week seems to be weak: tailoring duration of antibiotic treatment in Gram-negative ventilator-associated pneumonia

Ignacio Martin-Loeches et al. Crit Care. .

Abstract

The optimal length of antimicrobial therapy has not been extensively studied for a great majority of infections and, in critically ill patients affected by ventilator-associated pneumonia, is a persisting and unsolved issue confronting clinicians. The integration of biomarkers, clinical judgment, and microbiologic eradication might help to define a shorter duration for some ventilator-associated pneumonia episodes due to non-fermenting Gram-negative bacilli, but until these strategies are implemented in clinical practice for individualizing antibiotic treatment, a short-course duration does not seem to tailor a long benefit.

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