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Comment
. 2013 Feb;10(2):68.
doi: 10.1038/nrclinonc.2013.1. Epub 2013 Jan 22.

Pharmacology: Structure-based design for selective inhibition lowers toxicity

Bryony Jones
Comment

Pharmacology: Structure-based design for selective inhibition lowers toxicity

Bryony Jones. Nat Rev Clin Oncol. 2013 Feb.
No abstract available

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Comment on

  • ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets.
    Souers AJ, Leverson JD, Boghaert ER, Ackler SL, Catron ND, Chen J, Dayton BD, Ding H, Enschede SH, Fairbrother WJ, Huang DC, Hymowitz SG, Jin S, Khaw SL, Kovar PJ, Lam LT, Lee J, Maecker HL, Marsh KC, Mason KD, Mitten MJ, Nimmer PM, Oleksijew A, Park CH, Park CM, Phillips DC, Roberts AW, Sampath D, Seymour JF, Smith ML, Sullivan GM, Tahir SK, Tse C, Wendt MD, Xiao Y, Xue JC, Zhang H, Humerickhouse RA, Rosenberg SH, Elmore SW. Souers AJ, et al. Nat Med. 2013 Feb;19(2):202-8. doi: 10.1038/nm.3048. Epub 2013 Jan 6. Nat Med. 2013. PMID: 23291630

References

    1. Nat Med. 2013 Feb;19(2):202-8 - PubMed

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