Stem cells: A metabolic switch

Comment

Kim Baumann. Nat Rev Mol Cell Biol. 2013 Feb.

. 2013 Feb;14(2):64-5.

doi: 10.1038/nrm3515.

No abstract available

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Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells.
Takubo K, Nagamatsu G, Kobayashi CI, Nakamura-Ishizu A, Kobayashi H, Ikeda E, Goda N, Rahimi Y, Johnson RS, Soga T, Hirao A, Suematsu M, Suda T. Takubo K, et al. Cell Stem Cell. 2013 Jan 3;12(1):49-61. doi: 10.1016/j.stem.2012.10.011. Cell Stem Cell. 2013. PMID: 23290136 Free PMC article.
Metabolic regulation by the mitochondrial phosphatase PTPMT1 is required for hematopoietic stem cell differentiation.
Yu WM, Liu X, Shen J, Jovanovic O, Pohl EE, Gerson SL, Finkel T, Broxmeyer HE, Qu CK. Yu WM, et al. Cell Stem Cell. 2013 Jan 3;12(1):62-74. doi: 10.1016/j.stem.2012.11.022. Cell Stem Cell. 2013. PMID: 23290137 Free PMC article.