Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Jun;36(6):1597-603.
doi: 10.2337/dc12-0767. Epub 2013 Jan 22.

Increasing incidence of type 1 diabetes in youth: twenty years of the Philadelphia Pediatric Diabetes Registry

Terri H Lipman  1 , Lorraine E Levitt Katz, Sarah J Ratcliffe, Kathryn M Murphy, Alexandra Aguilar, Iraj Rezvani, Carol J Howe, Shruti Fadia, Elizabeth Suarez
Affiliations

Increasing incidence of type 1 diabetes in youth: twenty years of the Philadelphia Pediatric Diabetes Registry

Terri H Lipman et al. Diabetes Care. 2013 Jun.

Abstract

Objective: The purpose of this study was to describe the incidence of type 1 diabetes in children in Philadelphia from 2000-2004, compare the epidemiology to the previous three cohorts in the Philadelphia Pediatric Diabetes Registry, and, for the first time, describe the incidence of type 2 diabetes.

Research design and methods: Diabetes cases were obtained through a retrospective population-based registry. Hospital inpatient and outpatient records were reviewed for cases of type 1 and type 2 diabetes diagnosed from 1 January 2000 to 31 December 2004. The secondary source of validation was the School District of Philadelphia. Time series analysis was used to evaluate the changing pattern of incidence over the 20-year period.

Results: The overall age-adjusted incidence rate in 2000-2004 of 17.0 per 100,000 per year was significantly higher than that of previous cohorts, with an average yearly increase of 1.5% and an average 5-year cohort increase of 7.8% (P = 0.025). The incidence in white children (19.2 per 100,000 per year) was 48% higher than in the previous cohort. Children aged 0-4 years had a 70% higher incidence (12.2 per 100,000 per year) than the original cohort; this increase was most marked in young black children. The overall age-adjusted incidence of type 2 diabetes was 5.8 per 100,000 per year and was significantly higher in black children.

Conclusions: The incidence of type 1 diabetes is rising among children in Philadelphia. The incidence rate has increased by 29% since the 1985-1989 cohort. The most marked increases were among white children ages 10-14 years and black children ages 0-4 years. The incidence of type 1 diabetes is 18 times higher than that of type 2 in white children but only 1.6 times higher in black children.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Incidence of type 1 diabetes by race/ethnicity and year. Gray line = white children; black line = black children; dashed line = Hispanic children.
Figure 2
Figure 2
Age-adjusted incidence rates for type 1 diabetes in four cohorts, 1985–2004. □ = white children; ■ = black children; ▨ = Hispanic children.
Figure 3
Figure 3
Incidence of type 1 diabetes by age and racial/ethnic group (white [top], black [middle], and Hispanic [bottom]) in four cohorts, 1985–2004. □ = 0–4 years old; ■ = 5–9 years old; ▨ = 10–14 years old.
Figure 4
Figure 4
Age-adjusted incidence rates for type 1 (■) vs. type 2 (▨) diabetes by racial/ethnic group.
See this image and copyright information in PMC

References

    1. WHO DIAMOND Project Group WHO Multinational Project for Childhood Diabetes. Diabetes Care 1990;13:1062–1068 - PubMed
    1. Libman IM, LaPorte RE, Becker D, Dorman JS, Drash AL, Kuller L. Was there an epidemic of diabetes in nonwhite adolescents in Allegheny County, Pennsylvania? Diabetes Care 1998;21:1278–1281 - PubMed
    1. Smith TL, Drum ML, Lipton RB. Incidence of childhood type I and non-type 1 diabetes mellitus in a diverse population: the Chicago Childhood Diabetes Registry, 1994 to 2003. J Pediatr Endocrinol Metab 2007;20:1093–1107 - PubMed
    1. Vehik K, Hamman RF, Lezotte D, et al. Increasing incidence of type 1 diabetes in 0- to 17-year-old Colorado youth. Diabetes Care 2007;30:503–509 - PubMed
    1. The Writing Group for the SEARCH for Diabetes in Youth Study Group Incidence of diabetes in youth in the United States. JAMA 2007;297:2716–2724 - PubMed